Publications

  • McPherson JG*, Bandres M (2019). Therapeutic intraspinal microstimulation differentially modulates neural transmission in spinal motor and pain pathways (in preparation). *corresponding author.
  • McPherson JG, Miller RR, Perlmutter SI, Fetz EE (2019). Operant conditioning of deep forebrain reward circuitry using an electrocorticogram-triggered recurrent neural-computer interface (in final preparation).
  • Smith AC, Albin SR, Wasielewski M, McPherson JG, Kim HE, Hoggarth MA, Hornby TG, Elliott JM (2019). Do persons with severe whiplash show weakness in their lower extremities? (In review). 
  • McPherson JG, Smith AC, Duben D, Wasielewski M, McMahon K, Parrish TB, Elliott JM (2018). Short- and long-term reproducibility of diffusion-weighted magnetic resonance imaging of lower extremity musculature in asymptomatic individuals and a comparison to individuals with spinal cord injury. BMC Musculoskelet. Disord. Dec. 6th; doi: 10.1186/s12891-018-2361-7.
  • McPherson JG, Stienen AH, Schmit BD, Dewald JPA (2018). Biomechanical parameters of the elbow stretch reflex in chronic hemiparetic stroke. Exp. Brain Res. Oct. 1st; doi: 10/1007/s00221-018-5389-x. 
  • McPherson JG, Ellis MD, Harden RN, Carmona C, Drogos JM, Heckman CJ, Dewald JPA (2018). Neuromodulatory inputs to motoneurons contribute to the loss of independent joint control in chronic moderate to severe hemiparetic stroke. Front. Neurol. Jun 21; 9:470.doi: 10.3389/fneur.2018.00470
  • McPherson JG, McPherson LM, Thompson CK, Ellis MD, Heckman CJ, Dewald JPA (2018). Altered neuromodulatory drive may contribute to exaggerated tonic vibration reflexes in chronic hemiparetic stroke. Front. Hum. Neurosci. Apr. 12(131). doi: 10.3389/fnhum.2018.00131.
  • McPherson JG, Chen A, Ellis MD, Yao J, Harden RN, Heckman CJ, Dewald JPA (2018). Progressive recruitment of contralesional cortico-reticulospinal pathways drives impairment post-stroke. J Physiol. Apr 1;596(7):1211-1225. doi: 10.1113/JP274968.
  • McPherson JG, Stienen AH, Drogos JM, Dewald JPA (2018). Modification of spastic stretch reflexes at the elbow by flexion synergy expression in individuals with chronic, hemiparetic stroke. Arch. Phys. Med. Rehabil. Mar;99(3):491-500. doi: 10.1016/j.apmr.2017.06.019
  • Smith AC, Weber KA, Parrish TB, Hornby TG, Tysseling VM, McPherson JG, Wasielewski M, Elliott JM (2017). Ambulatory function in motor incomplete spinal cord injury: a magnetic resonance imaging study of spinal cord edema and lower extremity muscle morphometry. Spinal Cord. doi: 10.1038/sc.2017.18.
  • Elliott JM, Sudarshan D, Haxie C, Hoggarth M, McPherson JG, Sparks C, Weber K (2016). Advancements in imaging technology: do they (or will they) equate to advancements in our knowledge of recovery in whiplash? Journal of Orthopedic and Sports Physical Therapy, 46(10):862-873.
  • Smith AC, Knikou M, Yelick K, Alexander A, Murnane M, Kristelis A, Houmpavlis P, McPherson JG, Wasielewski M, Hoggarth M, Elliott (2016). MRI measures of fat infiltration in lower extremities following motor incomplete spinal cord injury: reliability and potential implications for muscle activation. IEEE Engineering in Medicine and Biology Society. Aug; 2016:5451-5456. doi: 10.1109/EMBC.2016.7591960.
  • Dewald JPA, Ellis MD, Acosta AM, McPherson JG, Stienen AH (2016). Implementation of impairment-based neurorehabilitation devices and technologies following brain injury. In: Dietz V, Reinkensmeyer DJ (eds.) Neurorehabilitation Technology: Springer, 2nd DOI: 10.1007/978-3-319-28603-7.
  • McPherson JG, Miller RR, Perlmutter SI (2015). Targeted, activity-dependent spinal stimulation produces long-lasting motor recovery in chronic cervical spinal cord injury. Proceedings of the National Academy of Sciences, 112(39):12193-8; DOI: 10.1073/pnas.1505383112.
  • Smith AC, Parrish TB, Hoggarth MA, McPherson JG, Tysseling VM, Wasielewski M, Kim HE, Hornby TG, Elliott JM (2015). Potential associations between chronic whiplash and incomplete spinal cord injury. Spinal Cord: Series and Cases, 2, pii: 15024.
  • McPherson JG, Edwards WB, Prasad A, Troy KL, Griffith JW, Schnitzer TJ (2014). Dual energy x-ray absorptiometry of the knee in individuals with spinal cord injury: methodology and correlation with quantitative computed tomography. Spinal Cord, 52(11): 821-5.
  • Dewald JPA, Ellis MD, Acosta AM, McPherson JG, Stienen AH, (2012). Implementation of impairment-based neurorehabilitation devices and technologies following brain injury. In: Dietz V, Nef T, Rymer Z (eds.) Neurorehabilitation Technology: Chapter 19: 343-358. Springer, 1st DOI: 10.1007/978-1-4471-2277-7.
  • McPherson JG, Stienen AH, Drogos JM, Dewald JPA (2011). The relationship between the flexion synergy and stretch reflexes in individuals with chronic hemiparetic stroke. IEEE International Conference on Rehabilitation Robotics: 5975516.
  • Stienen AH, McPherson JG, Schouten AC, Dewald JPA (2011). The ACT-4D: a novel rehabilitation robot for the quantification of upper limb motor impairments following brain injury. IEEE International Conference on Rehabilitation Robotics: 5975460.
  • McPherson JG, Ellis MD, Heckman CJ, Dewald JPA (2008). Evidence for increased activation of persistent inward currents in individuals with chronic hemiparetic stroke. Journal of Neurophysiology, 100: 3236-3243.

Press

  • “New research on the brain’s backup motor systems could open door to novel stroke therapies.” EurekAlert!(American Association for the Advancement of Science; AAAS). Feb. 14th, 2018.
  • “Study could lead to new therapies to improve movement control in stroke survivors.” The Medical News. Feb. 16th, 2018.
  • “New insights into stroke treatment.” Medindia. Feb. 16th, 2018.
  • Ozpinar A, Tempel ZJ, Monaco EA 3rd. “Targeted, activity-dependent spinal stimulation produces long-lasting motor recovery in chronic cervical spinal cord injury.” Commentary in 2016 Feb; 78(2): N18-9. doi: 10.1227/01.neu.0000479893.25489.47. 
  • Nudo, RJ. “Rehabilitation: Boost for movement.” Nature, 527: 314-315, Sept 19th, 2015.
  • “Electric zaps help spinal-cord rehab.” Nature, 525: 428. Sept 24, 2015.
  • “New electrostatic stimulation technique improves damaged nerve function in rats.” Medical Xpress, Sept 15th, 2015.
  • “Stimulating damaged spines rewires rats for recovery.” IEEE Spectrum, Sept 14th, 2015.

Support

Active

  • AHA: 19IPLOI34760603 (Innovative Project Award). McPherson (PI). “Restorative neuroplasticity in brainstem motor pathways to enhance rehabilitation post-stroke.” 
  • NIH/NINDS: 1 R01 NS111234-01. McPherson (PI). “Intraspinal microstimulation for multimodal rehabilitation.”
  • NIH/NICHD: K12HD073945. McPherson (PI). “Spinal stimulation for neuropathic pain.”
  • Coulter Foundation: SEED Grant. McPherson/Danziger/Hutcheson (PIs). “Exploring neural contributions to aortic valve function and disease.”
  • Coulter Foundation: SEED Grant: McPherson/McPherson/Danziger (PIs): “Non-invasive decoding of neuromuscular activity for rehabilitation and prosthetic control.”
  • Craig H. Neilsen Foundation: SCIRTS Grant. Danziger (PI). “Post-SCI bladder reflex conditioning with pelvic neuromodulation.” Role: co-investigator.

Completed

  • NIH/NICHD: R01 HD079076-01A1. Elliott (PI). “Neuromuscular mechanisms underlying poor recovery from whiplash injuries.” Role: post-doctoral research associate.
  • Raymond and Beverly Sackler Foundation. McPherson (PI). “Development of flexible, biocompatible electrode arrays for chronic stimulation of the central nervous system following neurological injury.”
  • NIH/NINDS: R01 NS054269 Dewald (PI). “Monoaminergic drive and discoordination followig stroke.” Role: graduate research associate.